ArticleFrontiers in neurology
Analysis of risk factors for hemorrhagic transformation after mechanical thrombectomy in acute anterior circulation large vessel occlusion stroke and construction of a nomogram prediction model.
Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Abstract
Objective: To identify risk factors for hemorrhagic transformation (HT) after mechanical thrombectomy (MT) in patients with acute anterior circulation large vessel occlusion (LVO) and to develop a predictive nomogram. Methods: This retrospective study enrolled 193 patients with acute anterior circulation LVO who underwent MT at a single center between January 2023 and December 2025. Patients were categorized into HT ( Results: Six independent risk factors for HT were identified: history of alcohol consumption (OR = 6.423, 95% CI 2.224-18.552, Conclusion: History of alcohol consumption, leukoencephalopathy, elevated GLR, D-dimer, and venous blood glucose, and reduced MPV are independent risk factors for HT after MT in acute anterior circulation LVO stroke. The constructed nomogram exhibits good discrimination, calibration, and clinical utility, providing a reliable tool for individualized risk prediction.
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