ArticleClinical parkinsonism & related disorders2026
Regional dopaminergic dysfunction patterns discriminate Parkinson's disease from multiple system atrophy parkinsonian subtype.
Article in Clinical parkinsonism & related disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Parkinson's disease (PD) and multiple system atrophy parkinsonian subtype (MSA-P) are clinically similar α-synucleinopathies, making differential diagnosis challenging. This study aimed to identify distinct regional dopaminergic dysfunction patterns using quantitative Methods: We prospectively recruited 20 PD patients, 12 MSA-P patients, and 9 healthy controls. All underwent Results: Both patient groups showed severe putaminal dopaminergic loss compared to controls. A key differentiator was caudate nucleus involvement: SUVR was significantly lower in MSA-P than in PD ( Conclusions:
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