Evidence map›Paper›PMID 42292914›Full record

ArticleMolecular therapy. Advances2026

Preclinical efficacy of a gene therapy for

Mahtab Tavasoli, Mariam Alkandari, Gabriel Dorighello, Jennifer Devitt, Laura Hagerty, Jesse Damsker, Eric P Hoffman, Christopher R McMaster

Abstract read
In one paragraph

Article in Molecular therapy. Advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mahtab TavasoliDepartment of Pharmacology, Dalhousie University, 5850 College St, Halifax, NS B3H 4H7, Canada.
Mariam AlkandariDepartment of Pharmacology, Dalhousie University, 5850 College St, Halifax, NS B3H 4H7, Canada.
Gabriel DorighelloDepartment of Pharmacology, Dalhousie University, 5850 College St, Halifax, NS B3H 4H7, Canada.
Jennifer DevittFaculty of Medicine, Dalhousie University, 5850 College St, Halifax, NS B3H 4H7, Canada.
Laura HagertyReveragen BioPharma Inc, 155 Gibbs St, Rockville MD 20850, USA.
Jesse DamskerReveragen BioPharma Inc, 155 Gibbs St, Rockville MD 20850, USA.
Eric P HoffmanReveragen BioPharma Inc, 155 Gibbs St, Rockville MD 20850, USA.
Christopher R McMasterDepartment of Pharmacology, Dalhousie University, 5850 College St, Halifax, NS B3H 4H7, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Loss-of-function variants of the

Indexed as

CHKBcholine kinasedystrophygene therapymusclemyopathyphosphatidylcholinephospholipid

Identifiers

PMID42292914
PMCPMC13263696

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.