Evidence map›Paper›PMID 42292876›Full record

ArticlePNAS nexus2026

The DdD protein confers intracellular and extracellular immunity to the leaderless bacteriocin enterocin DD14.

Clémence Cochard, Adrián Pérez-Ramos, Mari Luz Mohedano, Mario García de Lacoba, Paloma López, Djamel Drider

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PNAS nexus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Clémence CochardUnité Mixte de Recherche (UMR) Transfrontalière BioEcoAgro INRAE 1158, Université de Lille, 59000 Lille, France.
Adrián Pérez-RamosUnité Mixte de Recherche (UMR) Transfrontalière BioEcoAgro INRAE 1158, Université de Lille, 59000 Lille, France.ORCID https://orcid.org/0000-0001-7238-0776
Mari Luz MohedanoDepartamento de Biotecnología, Centro de Investigaciones Biológicas Margarita Salas (CIB, CSIC), 28040 Madrid, Spain.ORCID https://orcid.org/0000-0001-6748-9443
Mario García de LacobaDepartamento de Bioinformatics y Biostatistics, Centro de Investigaciones Biológicas Margarita Salas (CIB, CSIC), 28040 Madrid, Spain.ORCID https://orcid.org/0000-0003-3485-8307
Paloma LópezDepartamento de Biotecnología, Centro de Investigaciones Biológicas Margarita Salas (CIB, CSIC), 28040 Madrid, Spain.ORCID https://orcid.org/0000-0001-8755-8952
Djamel DriderUnité Mixte de Recherche (UMR) Transfrontalière BioEcoAgro INRAE 1158, Université de Lille, 59000 Lille, France.ORCID https://orcid.org/0000-0002-3113-1578

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leaderless bacteriocins (LBBs) are ribosomally synthesized antimicrobial peptides that differ from classical bacteriocins because they are produced in their active form without leader peptides. This raises the key biological question of how producing strains protect themselves from their own bacteriocins during synthesis and prior to secretion. Enterocin DD14 (EntDD14) is a two-peptide LBB produced by

Indexed as

DdD proteinenterocin 14immunityleaderless bacteriocinsself-protection

Identifiers

PMID42292876
PMCPMC13262744

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.