Evidence map›Paper›PMID 42292766›Full record

ArticlePhotoacoustics2026

An ingestible light source for deep photoacoustic imaging.

David C Garrett, Lihong V Wang

Abstract read
In one paragraph

Article in Photoacoustics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

David C GarrettCaltech Optical Imaging Laboratory, Andrew and Peggy Cherng Department of Medical Engineering, Department of Electrical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Lihong V WangCaltech Optical Imaging Laboratory, Andrew and Peggy Cherng Department of Medical Engineering, Department of Electrical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photoacoustic tomography leverages ultrasound's deep tissue penetration to retrieve optical absorption contrast well beyond the optical diffusion limit. Conventional photoacoustic systems rely on externally delivered light and are therefore constrained by optical attenuation, limiting imaging depths to several centimeters. Here, we overcome this constraint using a compact, acoustically powered device that provides optical excitation directly from within the target medium. By exploiting the weak attenuation of low-MHz ultrasound, acoustic energy is transmitted through tissue to wirelessly power a pulsed laser diode. The emitted light pulses generate photoacoustic signals that encode local optical absorption at clinically relevant depths, which could enable imaging in regions such as the gastrointestinal tract that are inaccessible to surface-based illumination. We demonstrate this approach by imaging through a 12 cm thick phantom, establishing a pathway toward deep-tissue photoacoustic imaging.

Indexed as

Acoustic power transferIngestibleLaser diodePhotoacoustic imaging

Identifiers

PMID42292766
PMCPMC13264102

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.