Evidence map›Paper›PMID 42292752›Full record

ArticleLaryngoscope investigative otolaryngology2026

Olfactory Outcomes After Endoscopic Sinus Surgery for Chronic Rhinosinusitis With Nasal Polyposis.

Elysia Grose, Jenny B Xiao, Patrick Macinnis, Yvonne Chan, John M Lee

Abstract read
In one paragraph

Article in Laryngoscope investigative otolaryngology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elysia GroseDivision of Rhinology, Department of Otolaryngology-Head and Neck Surgery, St. Michael's Hospital, Unity Health Toronto University of Toronto Toronto Ontario Canada.ORCID https://orcid.org/0000-0002-3054-3474
Jenny B XiaoDivision of Rhinology, Department of Otolaryngology-Head and Neck Surgery, St. Michael's Hospital, Unity Health Toronto University of Toronto Toronto Ontario Canada.
Patrick MacinnisDivision of Rhinology, Department of Otolaryngology-Head and Neck Surgery, St. Michael's Hospital, Unity Health Toronto University of Toronto Toronto Ontario Canada.
Yvonne ChanDivision of Rhinology, Department of Otolaryngology-Head and Neck Surgery, St. Michael's Hospital, Unity Health Toronto University of Toronto Toronto Ontario Canada.ORCID https://orcid.org/0000-0002-8502-3214
John M LeeDivision of Rhinology, Department of Otolaryngology-Head and Neck Surgery, St. Michael's Hospital, Unity Health Toronto University of Toronto Toronto Ontario Canada.ORCID https://orcid.org/0000-0001-8473-4674

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate subjective and objective olfactory outcomes in patients undergoing endoscopic sinus surgery (ESS) for chronic rhinosinusitis with nasal polyps (CRSwNP). Methods: Prospective, single-center study including adult patients undergoing ESS for CRSwNP from July 2022 to May 2024. Olfactory status was assessed using the Sinonasal Outcome Test (SNOT-22) and Sniffin' Sticks odor identification test preoperatively and at 1-, 3-, and 6-months postoperatively. Results: Thirty-six patients (45% female, mean age: 48 ± 14) were included. Among them, 47% had asthma, 53% had a history of previous sinus surgery, and 28% had aspirin-exacerbated respiratory disease. Mean SNOT-22 score decreased from 57 ± 20 to 22 ± 18, 15 ± 14, and 25 ± 19, at 1-, 3-, and 6-months postoperatively, respectively ( Conclusion: This prospective study demonstrates improvements in subjective and objective measures of olfaction after ESS in patients with CRSwNP. While the sense of smell may be the most difficult symptom to address with surgical intervention, our study provides direct evidence that appropriate surgical intervention can in fact provide meaningful improvements to a large proportion of patients with nasal polyps. Longer-term studies will be required to determine if these improvements will remain sustained. Level of Evidence: 3.

Indexed as

chronic rhinosinusitisendoscopic sinus surgeryolfaction

Identifiers

PMID42292752
PMCPMC13261535

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.