ArticleTranslational pediatrics2026
The disease burden of inguinal, femoral, and abdominal hernias in children from low- and middle-income countries, 1990-2023 with projections to 2050: a systematic analysis of the Global Burden of Disease Study.
Article in Translational pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Inguinal, femoral, and abdominal hernias (IFAH) are common and treatable pediatric surgical conditions, but delayed diagnosis and limited access to timely surgery may cause preventable death and disability in low-and middle-income countries (LMICs). This study aimed to assess the epidemiological trends and burden of IFAH among children aged 0-14 years in LMICs from 1990 to 2023. Methods: Based on the Global Burden of Disease 2023 data, we analyzed incidence, mortality, and disability-adjusted life years (DALYs) across 93 LMICs. Statistical analyses included trend assessment, decomposition, frontier analysis, and Bayesian age-period-cohort modeling to project future burden. Results: In 2023, LMICs accounted for 58.4% of global pediatric IFAH cases, with 83.8% of deaths and 74.0% of DALYs. While age-standardized rates declined in most regions since 1990, absolute incident cases rose in low Socio-demographic Index (SDI) regions. Infants under one year accounted for over 85% of deaths and males experienced a higher overall burden. Decomposition analysis indicated that epidemiological improvements were partially offset by population growth and aging. Health system performance varied, with countries like Myanmar and Haiti showing inefficiencies, while Somalia and Vanuatu performed better relative to resources. Projections suggest that by 2050, low SDI regions will face a continued rise in cases despite reductions elsewhere. Conclusions: Despite overall declines, significant inequalities persist in the burden of pediatric hernias across LMICs. Future efforts should prioritize early screening, surgical access for infants and children in low SDI regions, and strengthening basic surgical systems to address population growth challenges.
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