ArticleFrontiers in bioengineering and biotechnology2026
Sustainable microalgae-based Docosahexaenoic Acid-Silver nanoparticles for biomedical applications.
Article in Frontiers in bioengineering and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
Introduction: Docosahexaenoic acid (DHA) is an essential omega-3 polyunsaturated fatty acid with well-established health benefits. However, its poor water solubility and high susceptibility to oxidation limit its application in the biomedical field. In this study, DHA was extracted and purified from the marine microalga Results: Microscopic characterization confirmed the formation of nanosized, predominantly spherical AgNPs with an effective surface association with DHA. SEM and TEM analyses demonstrated distinct morphological changes following DHA loading, whereas XRD revealed reduced crystallinity, indicating surface modification. FTIR spectroscopy further confirmed the interactions between the DHA functional groups and the AgNP surface. Discussion: This study demonstrates a sustainable approach for producing microalgae-derived DHA-loaded AgNPs with enhanced structural stability and multifunctional properties. DHA-AgNPs, developed for biomedical applications, combine antimicrobial activity with improved DHA delivery and support the development of green nanomedicines.
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