ArticleIDCases2026
Isolation of
Article in IDCases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Burkholderia cepacia complex (BCC) comprises environmental non-fermenting Gram-negative bacilli that primarily cause opportunistic infections in immunocompromised individuals. Pericardial infection due to BCC is exceedingly rare, particularly in patients with malignancy. Differentiating infectious from malignant effusions remains a diagnostic challenge, especially in tuberculosis-endemic regions. Case presentation: We report a case of a 50-year-old female presenting with chronic cough, fever, and progressive Grade III dyspnoea requiring oxygen support. Imaging revealed right pleural effusion and pericardial effusion. Cytological examination of pleural fluid demonstrated malignant cells, and immunohistochemistry confirmed lung adenocarcinoma with metastasis. The patient was also HBsAg positive with detectable viral load, representing an additional immunocompromised state.Pericardial fluid culture isolated Burkholderia cepacia complex, while pleural fluid cultures remained sterile. Tuberculosis workup, including Ziehl-Neelsen staining, GeneXpert testing, and adenosine deaminase levels, was negative. Antimicrobial susceptibility testing performed using CLSI 2024 interpretative criteria demonstrated susceptibility to trimethoprim-sulfamethoxazole, levofloxacin, and meropenem; intermediate susceptibility to minocycline; and resistance to ceftazidime. The patient received targeted antimicrobial therapy along with chemotherapy and showed symptomatic improvement with reduced oxygen requirement. Discussion: Isolation of BCC from a sterile site without prior cardiac intervention raises important questions regarding pathogenesis. Dual immunocompromised states-lung adenocarcinoma with metastasis and chronic hepatitis B infection-likely facilitated opportunistic infection through hematogenous or contiguous spread. Clinical correlation and therapeutic response supported true infection rather than contamination. Conclusions: BCC can rarely cause pericardial infection in patients with malignancy. Comprehensive microbiological evaluation of pericardial fluid is essential even in confirmed malignant effusions to enable accurate diagnosis and targeted therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.