Evidence map›Paper›PMID 42292501›Full record

ArticleEuropean heart journal. Imaging methods and practice2026

High resolution, 3D isotropic late gadolinium enhanced imaging for the quantification of left atrial fibrosis and post-ablation scarring.

Maximilian Fenski, Richard Hickstein, Leo Dyke Krüger, Clemens Ammann, Thomas Hadler, Karl Kunze, Michaela Schmidt, René M Botnar, Claudia Prieto, André Rudolph and 4 more

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In one paragraph

Article in European heart journal. Imaging methods and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Maximilian FenskiExperimental and Clinical Resarch Center, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Lindenberger Weg 80, 13125 Berlin, Germany.ORCID https://orcid.org/0000-0002-5943-305X
Richard HicksteinExperimental and Clinical Resarch Center, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Lindenberger Weg 80, 13125 Berlin, Germany.ORCID https://orcid.org/0009-0009-7247-5076
Leo Dyke KrügerExperimental and Clinical Resarch Center, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Lindenberger Weg 80, 13125 Berlin, Germany.ORCID https://orcid.org/0009-0000-6595-1964
Clemens AmmannExperimental and Clinical Resarch Center, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Lindenberger Weg 80, 13125 Berlin, Germany.ORCID https://orcid.org/0000-0002-5962-4008
Thomas HadlerExperimental and Clinical Resarch Center, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Lindenberger Weg 80, 13125 Berlin, Germany.ORCID https://orcid.org/0000-0002-6151-6858
Karl KunzeResearch & Clinical Translation, Magnetic Resonance, Siemens Healthcare Limited, Camberley, UK.ORCID https://orcid.org/0000-0001-6403-2712
Michaela SchmidtResearch & Clinical Translation, Magnetic Resonance, Siemens Healthineers AG, Erlangen, Germany.
René M BotnarSchool of Biomedical Engineering, King´s College London, London, UK.
Claudia PrietoSchool of Biomedical Engineering, King´s College London, London, UK.
André RudolphDepartment for Cardiology and Nephrology, HELIOS Hospital Berlin-Buch, Schwanebecker Chaussee 50, 13125 Berlin, Germany.
Marcel ProthmannDepartment for Cardiology and Nephrology, HELIOS Hospital Berlin-Buch, Schwanebecker Chaussee 50, 13125 Berlin, Germany.
Michael WiedemannDepartment for Cardiology and Nephrology, HELIOS Hospital Berlin-Buch, Schwanebecker Chaussee 50, 13125 Berlin, Germany.
Thomas H GrandyDepartment for Cardiology and Nephrology, HELIOS Hospital Berlin-Buch, Schwanebecker Chaussee 50, 13125 Berlin, Germany.ORCID https://orcid.org/0000-0002-3574-6975
Jeanette Schulz-MengerExperimental and Clinical Resarch Center, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Lindenberger Weg 80, 13125 Berlin, Germany.ORCID https://orcid.org/0000-0003-3100-1092

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: Left atrial (LA) myopathy is a key driver of atrial fibrillation (AF) development and progression. Late gadolinium enhancement (LGE) cardiovascular magnetic resonance enables non-invasive quantification of LA fibrosis, a hallmark of atrial myopathy. However, conventional LGE sequences lack sufficient spatial resolution to accurately depict the thin atrial wall, and reference data in healthy cohorts are scarce. This study aimed to evaluate a high-resolution isotropic 3D LGE Dixon sequence for assessing LA fibrosis in healthy controls and AF patients. Methods and results: In this prospective study, 40 ablation-naïve AF patients (21 paroxysmal, 19 persistent) and 20 healthy controls underwent isotropic (1.3 mm Conclusion: High resolution isotropic 3D LA-LGE enables robust detection of ablation-induced scarring and biologically plausible fibrosis differences between AF stages. However, its correlation with bipolar voltage mapping remains limited, suggesting that LGE and EAM provide complementary information on atrial myopathy.

Indexed as

atrial fibrillationcardiovascular magnetic resonanceelectroanatomical mappinglate gadolinium enhancementleft atrial fibrosisleft atrial myopathy

Identifiers

PMID42292501
PMCPMC13262537

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.