Evidence map›Paper›PMID 42292490›Full record

ReviewFrontiers in immunology2026

Dynamics of HIV reservoirs following repeated anti-SARS-CoV-2 vaccination.

Jessica Lu, Ali Ahmad, Nicolas Chomont, Cecilia T Costiniuk

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jessica LuFaculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada.
Ali AhmadDepartment of Microbiology, Immunology & Infectious Diseases, Centre Hospitalier Universitaire (CHU) Sainte-Justine Research Center, University of Montreal, Montreal, QC, Canada.
Nicolas ChomontDépartement de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, QC, Canada.
Cecilia T CostiniukInfectious Diseases and Immunity in Global Health, Research Institute of McGill University Health Centre, Montreal, QC, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to persistent immune dysfunction, People with HIV (PWH) are at increased risk of more severe infections with SARS-CoV-2 and hospitalizations. In several countries, they were listed as a priority group for receiving anti-SARS-CoV-2 vaccines when these vaccines were in scarce supply. These prophylactic vaccines do not completely prevent infections in vaccinated individuals, especially with a heterologous vaccine strain. However, they persistently reduce the severity of breakthrough infections, hospitalization rates and deaths. Although antiretroviral therapy (ART) suppresses HIV replication below the levels detectable by the assays used routinely in clinical care, it does not eliminate viral reservoirs; a small pool of infected cells carrying HIV proviruses integrated into the genomes of CD4

Indexed as

COVID-19COVID-19 VaccinesHIV-1HIV InfectionsSARS-CoV-2CD4-Positive T-LymphocytesDisease ReservoirsHumansVaccinationVirus ActivationVirus LatencyCOVID-19 VaccinesHIVHIV reservoirsinflammationPWHSARS-CoV-2vaccination

Identifiers

PMID42292490
PMCPMC13260501

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.