Evidence map›Paper›PMID 42292269›Full record

ArticleFrontiers in medicine2026

Patterns and prevalence of ophthalmic self-medication in Bulgaria: results from a cross-sectional survey.

Mladena Radeva, Elitsa Hristova, Andreas Kontny, Zornitsa Zlatarova, Igor Resnick

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In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Mladena RadevaMedical University of Varna, Varna, Bulgaria.
Elitsa HristovaMedical University of Varna, Varna, Bulgaria.
Andreas KontnyMedical University of Varna, Varna, Bulgaria.
Zornitsa ZlatarovaMedical University of Varna, Varna, Bulgaria.
Igor ResnickMedical University of Varna, Varna, Bulgaria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Ophthalmic self-medication, defined as the use of over-the-counter eye medications without prescription, represents a significant public health concern due to potential complications such as delayed diagnosis, antimicrobial resistance, and vision impairment. Despite its global prevalence, data on this practice in Bulgaria remain limited. This study aimed to comprehensively assess the prevalence, patterns, determinants, and self-reported outcomes of ophthalmic self-medication among adults in Bulgaria. Methods: A cross-sectional online survey was conducted between March and May 2025 among adults aged ≥18 years residing in Bulgaria. An anonymous questionnaire comprising 15 items assessed sociodemographic characteristics, ocular complaints, motivations for self-medication, perceived safety and knowledge, and self-reported outcomes. A total of 1,000 respondents were included in the analysis. Descriptive statistics and inferential analyses (Pearson's chi-square and Fisher's exact test with Monte Carlo simulation) were performed, with statistical significance set at Results: The sample was predominantly female (90.8%), aged 31-50 years (75.6%), highly educated (85.1%), and employed (83.1%). The prevalence of ophthalmic self-medication was 63.7%. The most common complaints were infectious conditions (37.3%) and dry-eye symptoms (23.1%). Primary motivations included lack of time to seek specialist care (41.1%) and the perception that consultation was unnecessary (33.7%). Most participants (66.2%) considered self-medication safe, while 39.6% reported poor or no knowledge of ophthalmic medications. Among self-treated respondents ( Conclusion: Ophthalmic self-medication was highly prevalent in this Bulgarian sample and was primarily driven by accessibility barriers and perceived low necessity for specialist consultation. Although adverse events were rarely reported, the discrepancy between perceived safety and self-assessed knowledge highlights potential risks. These findings underscore the need for targeted patient education, improved access to ophthalmic care, and pharmacist-supported referral strategies to promote safer self-care practices.

Indexed as

Bulgariaonline surveyophthalmologyself-medicationself-treatment

Identifiers

PMID42292269
PMCPMC13259647

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