ArticleFrontiers in medicine2026
Waist-to-height ratio for OSA risk: a comparative analysis of NHANES and a clinical data.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: This study aims to demonstrate the relationship between waist-to-height ratio (WHtR) and obstructive sleep apnea (OSA) risk by analyzing data from the National Health and Nutrition Examination Survey (NHANES) and clinical cases. Methods: This study utilized data from the National Health and Nutrition Examination Survey (NHANES), a nationally representative cross-sectional survey of the US non-institutionalized population, and a retrospective clinical dataset of 200 patients who underwent polysomnography (PSG) at the Sleep Center of Tianjin Chest Hospital, China. Multivariate logistic regression analysis, restricted cubic spline (RCS) analysis, receiver operating characteristic (ROC) curves and subgroup analysis were used to assess the association between WHtR and the OSA risk. Results: WHtR was positively associated with OSA risk in both datasets. In the adjusted model, each 0.1-unit increase in WHtR was associated with higher odds of OSA (NHANES: OR 2.780, 95% CI: 2.536-3.048; clinical: OR 11.998, 95% CI: 6.010-23.953; both Conclusions: WHtR is a strong indicator of an increased OSA risk. WHtR has superior predictive value for OSA compared to BMI in clinical data, but shows equivalence in population data. WHtR demonstrates promise as a screening tool in a high-prevalence, clinically referred Chinese population.
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