ArticleFrontiers in medicine2026
Beyond the pelvis: diagnostic and surgical challenges of thoracic endometriosis syndrome - a retrospective cohort study of 41 patients.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: This study provides a comprehensive analysis of surgically managed thoracic endometriosis syndrome (TES) patients, primarily assessing whether diaphragmatic reconstruction is associated with lower postoperative recurrence. Secondarily, the study aims to evaluate histopathological findings and temporal changes in management of TES at a tertiary care center. Methods: This retrospective study of 41 female patients (median age 37) treated surgically for TES between 2012 and 2025 at the Department of Thoracic Surgery, Medical University of Gdansk, Poland. Patients presenting with pneumothorax and/or symptoms of diaphragmatic endometriosis were stratified into Early and Late periods to evaluate changes in surgical management - video-assisted thoracoscopic surgery (VATS), thoracotomy, thoracolaparoscopy, and the implementation of accurate immunohistochemical histopathological assessment. Results: Complete follow-up was available for 78.0% of patients, however, with differential loss to follow-up between groups (4.5% reconstruction vs. 42.1% no reconstruction; Conclusion: In the study, diaphragmatic reconstruction was associated with lower intervention-requiring recurrence, which may indicate a potential benefit of reconstructive techniques in TES surgery. Routine immunohistochemical evaluation (ER, PR, CD10) may be essential for TES diagnosis.
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