Evidence map›Paper›PMID 42292168›Full record

ArticleAmerican journal of ophthalmology case reports2026

Bilateral lens subluxation in a patient with homocystinuria: a case report.

Zongyi Zhan, Jiachun Cai, Jiaming Wang, Xin Liu, Danyao Nie, Dahui Ma

Abstract read
In one paragraph

Article in American journal of ophthalmology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zongyi ZhanShenzhen Eye Hospital, Shenzhen Eye Medical Center, Southern Medical University, Shenzhen, China.
Jiachun CaiShenzhen Eye Hospital, Shenzhen Eye Medical Center, Southern Medical University, Shenzhen, China.
Jiaming WangShenzhen Eye Hospital, Shenzhen Eye Medical Center, Southern Medical University, Shenzhen, China.
Xin LiuShenzhen Eye Hospital, Shenzhen Eye Medical Center, Southern Medical University, Shenzhen, China.
Danyao NieShenzhen Eye Hospital, Shenzhen Eye Medical Center, Southern Medical University, Shenzhen, China.
Dahui MaShenzhen Eye Hospital, Shenzhen Eye Medical Center, Southern Medical University, Shenzhen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To report a case of bilateral lens subluxation associated with homocystinuria that had been previously misdiagnosed with high myopia, amblyopia, and keratoconus. Observations: A 19-year-old Asian female presented with progressive bilateral visual decline and hand tremors over 10 years. Slit-lamp examination, anterior segment optical coherence tomography, genetic and metabolic testing were performed to confirm the diagnosis of homocystinuria. Surgical intervention was undertaken to improve visual acuity. Anterior segment imaging documented bilateral lens subluxation and microspherophakia before and after intraocular lens suture fixation surgery. Postoperatively, her vision improved to 20/20. Conclusions and importance: This case demonstrates the importance of basic slit-lamp examination especially after cycloplegic refraction for unusual myopia progression and the need to recognize associated systemic symptoms in ophthalmic practice.

Indexed as

HomocystinuriaLens subluxation

Identifiers

PMID42292168
PMCPMC13254709

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.