Evidence map›Paper›PMID 42292127›Full record

ArticleJTCVS techniques2026

Evaluating the feasibility of a novel device for enhanced control of chordal length assessment in mitral valve surgery: A porcine model study.

Thomas Poschner, Gianluca Dimonte, Markus Mach, Andrei-Antonio Caracioni, Thomas Putz, Sahra Tasdelen, Siya Saidian, Robert E Bartz, Jude S Sauer, Martin Andreas

Abstract read
In one paragraph

Article in JTCVS techniques, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Thomas PoschnerDivision of Cardiac Surgery, Medical University of Graz, Graz, Austria.
Gianluca DimonteChristian Doppler Laboratory for Microinvasive Heart Surgery, Division of Cardiac Surgery, Medical University of Graz, Graz, Austria.
Markus MachDivision of Cardiac Surgery, Medical University of Graz, Graz, Austria.
Andrei-Antonio CaracioniDivision of Cardiac Surgery, Medical University of Graz, Graz, Austria.
Thomas PutzDivision of Cardiac Surgery, Medical University of Graz, Graz, Austria.
Sahra TasdelenChristian Doppler Laboratory for Microinvasive Heart Surgery, Division of Cardiac Surgery, Medical University of Graz, Graz, Austria.
Siya SaidianLSI SOLUTIONS, Victor, NY.
Robert E BartzLSI SOLUTIONS, Victor, NY.
Jude S SauerLSI SOLUTIONS, Victor, NY.
Martin AndreasDivision of Cardiac Surgery, Medical University of Graz, Graz, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Determining the appropriate expanded polytetrafluoroethylene (ePTFE) chord length remains a critical step in mitral valve repair. Freehand ePTFE suturing and premeasured loops are widely used but present technical challenges. A novel chordal holder device was developed to temporarily secure the ePTFE suture during pressurized saline infusion testing, enabling precise subsequent adjustment of chordal length. This feasibility study evaluated this technology in an ex vivo porcine heart model. Methods: In 20 ex vivo porcine hearts, Carpentier type II mitral regurgitation was induced by cutting chordae tendineae in the A2 and/or P2 segments. An LS-5 ePTFE suture was placed using the Mi-STITCH Device. The study technology temporarily held the ePTFE suture at a desired length during infusion testing. Once optimal coaptation was achieved, the chord was permanently secured with a customized Mi-KNOT titanium fastener. Times for suture placement, length adjustment, knot fixation, and total implantation were recorded. Results: A total of 37 ePTFE sutures were implanted. The chordal holder provided reliable temporary fixation and facilitated readjustment with no suture damage. Median time for valve repair was 3 minutes, 20 seconds (02:21; 5:14), with 1 to 4 ePTFE suture placements required to achieve adequate repair. Procedural times did not differ between isolated and nonisolated P2 prolapse ( Conclusions: Setting appropriate replacement chordal length with the evaluated technology is fast, feasible, and intuitive. The chordal holder enabled precise length adjustment and competent repairs. These encouraging results support further evaluation in clinical settings.

Indexed as

chordal replacementePTFEmitral regurgitationmitral valve repairnovel devicepreclinical study

Identifiers

PMID42292127
PMCPMC13261156

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.