Evidence map›Paper›PMID 42292100›Full record

ArticleJTCVS techniques2026

Transpericardial ultrasound-guided management of visceral malperfusion in acute type A aortic dissection.

Veronica Lorenz, Giulio Tommasino, Luigi Muzzi, Enrico Tucci, Eugenio Neri

Abstract read
In one paragraph

Article in JTCVS techniques, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Veronica LorenzCardiac Surgery Unit, Department of Medicine, Surgery, and Neuroscience, University of Study of Siena, Siena, Italy.
Giulio TommasinoCardiac Surgery Unit, Department of Medicine, Surgery, and Neuroscience, University of Study of Siena, Siena, Italy.
Luigi MuzziCardiac Surgery Unit, Department of Medicine, Surgery, and Neuroscience, University of Study of Siena, Siena, Italy.
Enrico TucciCardiac Surgery Unit, Department of Medicine, Surgery, and Neuroscience, University of Study of Siena, Siena, Italy.
Eugenio NeriCardiac Surgery Unit, Department of Medicine, Surgery, and Neuroscience, University of Study of Siena, Siena, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Visceral malperfusion remains a major determinant of early mortality in acute type A aortic dissection. Rapid identification and classification of malperfusion mechanisms are crucial to guide treatment decisions and improve outcomes. Methods: We retrospectively analyzed 108 patients undergoing surgical repair for acute type A aortic dissection. Transpericardial ultrasound was performed intraoperatively in 75 patients at 1 or more timepoints (pre-, intra-, or postcardiopulmonary bypass). Visceral flow in the superior mesenteric artery and celiac trunk was graded semiquantitatively. Flow improvement after cardiopulmonary bypass was considered diagnostic of dynamic malperfusion. Postoperative outcomes and causes of death were analyzed in relation to perfusion trends. Results: Visceral malperfusion was diagnosed in 26 patients (24.1%). Superior mesenteric artery flow normalized intraoperatively in 22 (84.6%), indicating dynamic obstruction. Patients with flow normalization had significantly lower mortality (9.1%) than those with persistent malperfusion (60%). Transpericardial ultrasound findings guided surgical decision making, supporting extended arch repair or endovascular adjuncts only when flow remained impaired. Thirty-day mortality was 22.2% overall, with multiorgan failure and ischemia accounting for most deaths in patients with malperfusion. Conclusions: Transpericardial ultrasound is a valuable tool for intraoperative assessment of visceral perfusion. It enables real-time distinction between reversible and irreversible malperfusion, supports a perfusion-guided repair-first strategy, and may reduce unnecessary interventions while improving risk stratification and outcomes.

Indexed as

acute type A aortic dissectiontranspericardial ultrasoundvisceral malperfusion

Identifiers

PMID42292100
PMCPMC13261167

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.