Evidence map›Paper›PMID 42292034›Full record

ArticleInternational journal of nanomedicine2026

Melittin-Loaded Fe

Wen Chao Xu, Xiao Qu Duan, Li Zhong, Yuan Chao Li, Lei Ran, Hai Huan Xu, Qian Wu, Ke Huang, Na Nan Miao, Tao Jiang and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of nanomedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Wen Chao Xu *Department of Radiology, Xinqiao Hospital, Army Medical University, Chongqing, 400037, People's Republic of China.
Xiao Qu Duan *Department of Rheumatology and Dermatology, Xinqiao Hospital, Army Medical University, Chongqing, 400037, People's Republic of China.ORCID 0009-0003-0753-788X
Li Zhong *National & Local Joint Engineering Research Center of Harbour Oil & Gas Storage and Transportation Technology/Zhejiang Key Laboratory of Pollution Control for Port-Petrochemical Industry, Zhejiang Ocean University, Zhoushan, 316022, People's Republic of China.
Yuan Chao LiDepartment of Rheumatology and Dermatology, Xinqiao Hospital, Army Medical University, Chongqing, 400037, People's Republic of China.ORCID 0009-0008-4219-3759
Lei RanDepartment of Rheumatology and Dermatology, Xinqiao Hospital, Army Medical University, Chongqing, 400037, People's Republic of China.
Hai Huan XuDepartment of Dermatology, Characteristic Medical center of Chinese People's Armed Police Force, Tianjin, 300162, People's Republic of China.
Qian WuDepartment of Rheumatology and Dermatology, Xinqiao Hospital, Army Medical University, Chongqing, 400037, People's Republic of China.
Ke HuangDepartment of Rheumatology and Dermatology, Xinqiao Hospital, Army Medical University, Chongqing, 400037, People's Republic of China.
Na Nan MiaoDepartment of Rheumatology and Dermatology, Xinqiao Hospital, Army Medical University, Chongqing, 400037, People's Republic of China.ORCID 0009-0004-0575-0908
Tao JiangDepartment of Rheumatology and Dermatology, Xinqiao Hospital, Army Medical University, Chongqing, 400037, People's Republic of China.ORCID 0009-0007-7979-9909
Qiu Han ChenDepartment of Rheumatology and Dermatology, Xinqiao Hospital, Army Medical University, Chongqing, 400037, People's Republic of China.
Yang ZhangDepartment of Rheumatology and Dermatology, Xinqiao Hospital, Army Medical University, Chongqing, 400037, People's Republic of China.
Hong Zhuang ZhangDepartment of Burns, Characteristic Medical Center of Chinese People's Armed Police Force, Tianjin, 300162, People's Republic of China.
Ru Peng WangDepartment of Rheumatology and Dermatology, Xinqiao Hospital, Army Medical University, Chongqing, 400037, People's Republic of China.ORCID 0009-0008-8209-9281
Mingfu GongDepartment of Radiology, Xinqiao Hospital, Army Medical University, Chongqing, 400037, People's Republic of China.ORCID 0000-0002-1079-6845

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Atopic dermatitis (AD) severely impairs the lives of patients and existing therapies are limited by side effects or insufficient efficacy. In this study, we developed a multifunctional nanocomposite hydrogel that integrates immunoregulation, antioxidant, antibacterial, and skin repair for the integrative treatment of AD. Methods: Fe Results: The Fe Conclusion: MFA@PF127 exhibited multifunctionality of immunoregulation, and antioxidant and antibacterial activities, which significantly alleviated AD symptoms in a mouse model and provided a potential strategy for AD treatment after further preclinical validation.

Indexed as

Dermatitis, AtopicHydrogelsMagnetite NanoparticlesMelittenNanocompositesAnimalsAnti-Bacterial AgentsAntioxidantsFemaleHaCaT CellsHumansMicePoloxamerReactive Oxygen SpeciesStaphylococcus aureusAnti-Bacterial AgentsAntioxidantsHydrogelsMagnetite NanoparticlesMelittenPoloxamerReactive Oxygen Speciesantibacterialimmunoregulationnanoparticlesphotothermal therapypluronic F127ROS

Identifiers

PMID42292034
PMCPMC13264410

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.