Evidence map›Paper›PMID 42292012›Full record

ArticleCureus2026

Rhinoscleroma Masquerading as a Nasal Mass: A Diagnostic Challenge in a Young Adult.

Rutuja Pandharmise, Vivek Harkare, Sonali P Khadakkar, Fahad I Idrees, Sanaya D Dholkawala

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rutuja PandharmiseOtolaryngology - Head and Neck Surgery, N. K. P. Salve Institute of Medical Sciences and Research, Nagpur, IND.
Vivek HarkareOtolaryngology - Head and Neck Surgery, N. K. P. Salve Institute of Medical Sciences and Research, Nagpur, IND.
Sonali P KhadakkarOtolaryngology - Head and Neck Surgery, N. K. P. Salve Institute of Medical Sciences and Research, Nagpur, IND.
Fahad I IdreesMedical Education, N. K. P. Salve Institute of Medical Sciences and Research, Nagpur, IND.
Sanaya D DholkawalaOtolaryngology - Head and Neck Surgery, N. K. P. Salve Institute of Medical Sciences and Research, Nagpur, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rhinoscleroma is a rare, chronic granulomatous disease of the upper respiratory tract caused by Klebsiella rhinoscleromatis. Although uncommon, it continues to persist in developing regions and often presents a diagnostic challenge due to its indolent course, nonspecific clinical features, and resemblance to other granulomatous or neoplastic conditions. We report the case of a 23-year-old male who presented with progressively worsening bilateral nasal obstruction, intermittent epistaxis, and persistent mucopurulent nasal discharge over a duration of six months. Endoscopic evaluation revealed multiple firm nodular lesions involving the nasal vestibule, septum, and extending to the hard palate, suggesting locally aggressive yet non-destructive pathology. Initial histopathological examination was inconclusive, demonstrating only nonspecific inflammatory changes. However, a repeat biopsy combined with immunohistochemical analysis confirmed the diagnosis. Radiological imaging showed a heterogeneously enhancing soft tissue lesion with smooth bony remodeling leading to near-total nasal obstruction, without evidence of bone destruction. The patient was managed with a combination of systemic corticosteroids and prolonged antimicrobial therapy, resulting in significant clinical improvement and regression of lesions. This case underscores the importance of maintaining a high index of suspicion in endemic areas, the diagnostic value of repeat biopsy, and the necessity of prolonged therapy to prevent recurrence and complications.

Indexed as

granulomatous diseaseklebsiella rhinoscleromatisnasal airway obstructionnasal cavity massrhinoscleroma

Identifiers

PMID42292012
PMCPMC13261613

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