Evidence map›Paper›PMID 42291995›Full record

ArticleCureus2026

A Case of Fulminant Infective Endocarditis in Mitral Valve Prolapse With Septic Emboli and an Annular Abscess.

Riley L Smith, Polsha Jules, Ryan Clark

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Riley L SmithDepartment of Internal Medicine, Liberty University College of Osteopathic Medicine (LUCOM), Lynchburg, USA.
Polsha JulesDepartment of Cardiology, Kettering Health Network, Dayton, USA.
Ryan ClarkDepartment of Cardiology, Kettering Health Network, Dayton, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitral valve prolapse (MVP) is associated with an increased risk of infective endocarditis (IE), particularly in patients with mitral regurgitation and leaflet thickening. Historically, a subset of patients with mitral valve prolapse were considered for antibiotic prophylaxis before dental procedures. Conversely, current recommendations limit prophylaxis to the highest-risk cardiac conditions, such as congenital heart defects, mechanical valves, heart transplant with valvular issues, and a history of IE. We present a case of a 59-year-old man with a history of MVP with mildly thickened posterior leaflet, hypertension, hyperlipidemia, and prior tobacco use who presented to the hospital with nausea and vomiting four weeks after a tooth extraction. Initial laboratory evaluation was notable for elevated inflammatory markers, elevated transaminases, hyperbilirubinemia, and elevated troponin levels. Blood cultures grew methicillin-sensitive

Indexed as

annular abscessantibiotic policies and guidelinescardiac abscessdental extractionendocarditisinfective endocarditismitral valve prolapsemitral valve replacementseptic emboli

Identifiers

PMID42291995
PMCPMC13263070

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.