Evidence map›Paper›PMID 42291979›Full record

ArticleCureus2026

Seeding the Spine: Salmonella Java Discitis and Osteomyelitis After Traveller's Bacteraemia.

Nazar Abdelgabar, Yahia Khalil, Layan Abu-Khalaf, Mohammad Khalil

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nazar AbdelgabarGastroenterology and Hepatology, St Mary's Hospital, Isle of Wight NHS Trust, Newport, GBR.
Yahia KhalilInternal Medicine, St Mary's Hospital, Isle of Wight NHS Trust, Newport, GBR.
Layan Abu-KhalafSchool of Medicine, Royal College of Surgeons in Ireland, Dublin, IRL.
Mohammad KhalilSchool of Medicine, Royal College of Surgeons in Ireland - Bahrain, Manama, BHR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-typhoidal Salmonella infection usually causes self-limiting gastroenteritis, but a minority of cases are complicated by bacteraemia and extraintestinal focal infection. Vertebral discitis and osteomyelitis are rare complications, most often described in patients with diabetes, haemoglobinopathy, or immunosuppression. We describe a 67-year-old man with hypertension and previous percutaneous coronary intervention who attended the emergency department five times over six weeks with fever, rigors, diarrhoea, and worsening thoracic back pain after travel to Sri Lanka and the Maldives. Blood cultures grew Salmonella Java susceptible to ceftriaxone, ciprofloxacin, and co-trimoxazole. Initial CT of the chest, abdomen, and pelvis was unremarkable. CT angiography performed several weeks later showed mid-thoracic vertebral destruction and disc space change. MRI confirmed severe T6-T7 discitis and osteomyelitis with prevertebral soft tissue involvement of the adjacent oesophagus and azygous vein, together with periaortic enhancement from T5/T6 to T9. CT angiography found no aortitis. A repeat echocardiogram showed no evidence of infective endocarditis. Treatment required several antimicrobial adjustments, including prolonged intravenous ceftriaxone and later oral step-down to amoxicillin. Back pain improved substantially and serial radiographs showed no vertebral collapse. This case illustrates that Salmonella Java can seed the spine without classical immunocompromising risk factors and that the diagnosis is often delayed when persistent back pain is initially attributed to travel-associated gastroenteritis. Recurrent or unresolved symptoms after a confirmed Salmonella bacteraemia warrant early spinal MRI.

Indexed as

rare salmonella presentationssalmonella bacteremiasalmonella enterica discitistravel-related infectionvertebral osteomyelitis

Identifiers

PMID42291979
PMCPMC13257745

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.