ArticleCureus2026
Rapid Antimicrobial Susceptibility Testing (RAST): A Quick Guide to Bacterial Sepsis Management.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Sepsis is a life-threatening condition that remains a major global health problem. Strengthening diagnostic stewardship is vital in combating sepsis. Administration of an antimicrobial agent based on a conventional antimicrobial susceptibility testing (AST) report requires about two days after a positive blood culture. In contrast, the European Committee on Antimicrobial Susceptibility Testing (EUCAST) Rapid Antimicrobial Susceptibility Testing (RAST) enables earlier antibiotic administration, reducing turnaround time (TAT) and improving survival. This study compares the reliability of RAST with standard AST (SAST) to establish RAST as a valuable diagnostic tool in our setting for managing bacterial sepsis. Materials and methods A prospective study (institutional ethics committee (IEC) number: RC/2023/53) was conducted in a tertiary care hospital. A total of 53 isolates were included in the study based on the inclusion criteria of monobacterial positive blood cultures. From a positively flagged blood culture bottle, Rapid Antimicrobial Susceptibility Testing (RAST) was performed, and the results of the eight-hour test were documented based on EUCAST RAST 2023 guidelines. Statistical analysis was performed using SPSS software version 29.0 (IBM Corp., Armonk, NY). Results Among the 53 isolates,
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