ArticleCureus2026
Cavitary Pulmonary Nodules in Rheumatoid Arthritis: A 17-Year Imaging Follow-Up of Necrobiotic Granulomas.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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3 authors.
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Abstract
Pulmonary necrobiotic granulomas are a rare extra-articular manifestation of rheumatoid arthritis (RA) that may radiographically mimic infection or malignancy. We present a 57-year-old woman with RA and a smoking history who was found to have subpleural cavitary pulmonary nodules on computed tomography (CT). A biopsy confirmed necrobiotic granulomas. Serial imaging over a 17-year period demonstrated a fluctuating course, including enlargement of lesions from 1.4 cm to 4.4 cm, development of new cavitary nodules, fluid-filled transformation, and partial spontaneous regression. Despite marked radiographic progression, the patient remained clinically stable and was managed conservatively with multidisciplinary follow-up. To our knowledge, such prolonged longitudinal imaging follow-up of rheumatoid pulmonary nodules is rare. This case highlights the prolonged and variable natural history of RA-associated pulmonary nodules and underscores the importance of recognizing their imaging characteristics to prevent unnecessary invasive intervention. Long-term surveillance may be appropriate in asymptomatic patients despite radiologic progression.
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