ArticleCureus2026
Bacterial Infections in Decompensated Cirrhosis: Clinical Profile, Microbiology, and Antimicrobial Resistance Patterns.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
9 authors.
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Abstract
Background Hospitalised patients with decompensated cirrhosis face a high risk of bacterial infections. Antimicrobial resistance (AMR) is increasing globally, yet prospective data from the Indian subcontinent - a recognised AMR hotspot - remain limited. Methods This prospective observational study enrolled 176 consecutively hospitalised adults with decompensated cirrhosis over 18 months (September 2022 to February 2024). We analysed clinical profiles, infection prevalence, microbiological isolates, antimicrobial susceptibility patterns, and in-hospital outcomes. Multivariate logistic regression identified independent predictors of infection and mortality. Results Bacterial infections were documented in 82 patients (46.6%). Infected patients were younger (mean age, 48.5 vs. 53.8 years) and predominantly male (76.8%), with higher disease severity (93.9% Child-Turcotte-Pugh (CTP) class C; 79.3% Model for End-Stage Liver Disease-sodium (MELD-Na) >21). In-hospital mortality was significantly higher in infected patients (31/82, 37.8%) compared with non-infected patients (3/94, 3.2%; p < 0.001). Culture positivity was 48.8% (40/82), with
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