Evidence map›Paper›PMID 42291788›Full record

ReviewNanoscale advances2026

Nanoporous-based biomaterials in biomedical applications: from fundamentals and biosensing to drug delivery, wound healing, and tissue engineering.

Zahra Saadatidizaji, Iman Zare, Mingzhen Zhang, Shahrzad Zirak Hassan Kiadeh, Mojdeh Mirshafiei, Amin Farahani, Zahra Sadat, Hooman Aghamirza Moghim Aliabadi, Mohammad Mahdavi, Reza Eivazzadeh-Keihan and 6 more

Abstract readReview
In one paragraph

Review in Nanoscale advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Zahra SaadatidizajiFaculty of Chemistry, University of Tabriz 51666-16471 Tabriz Iran.
Iman ZareResearch and Development Department, Sina Medical Biochemistry Technologies Co., Ltd. Shiraz 7178795844 Iran.ORCID https://orcid.org/0000-0002-0056-5576
Mingzhen ZhangSchool of Basic Medical Sciences, Xi'an Jiaotong University Xi'an Shaanxi 710061 China.ORCID https://orcid.org/0000-0002-4686-6526
Shahrzad Zirak Hassan KiadehNew Technologies Research Center (NTRC), Amirkabir University of Technology (Tehran Polytechnic) Tehran Iran.ORCID https://orcid.org/0000-0002-8798-8255
Mojdeh MirshafieiDepartment of Biotechnology, School of Chemical Engineering, College of Engineering, University of Tehran Tehran Iran.
Amin FarahaniCellular and Molecular Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences Tehran Iran.
Zahra SadatEndocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences Tehran Iran reza_eivazzadeh@chem.iust.ac.ir amir.inventor@gmail.com.
Hooman Aghamirza Moghim AliabadiAdvanced Chemical Studies Lab, Department of Chemistry, K. N. Toosi University of Technology Tehran Iran.ORCID https://orcid.org/0000-0003-2150-5721
Mohammad MahdaviEndocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences Tehran Iran reza_eivazzadeh@chem.iust.ac.ir amir.inventor@gmail.com.
Reza Eivazzadeh-KeihanEndocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences Tehran Iran reza_eivazzadeh@chem.iust.ac.ir amir.inventor@gmail.com.
Amir KashtiarayEndocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences Tehran Iran reza_eivazzadeh@chem.iust.ac.ir amir.inventor@gmail.com.
Parisa RezvaniFaculty of Paramedical Sciences, Tehran Medical Sciences, Islamic Azad University Tehran Iran.
Aisan YahyapoorFaculty of Paramedical Sciences, Tehran Medical Sciences, Islamic Azad University Tehran Iran.
Amirali VaziriFaculty of Veterinary Medicine, Islamic Azad University Alborz Iran.ORCID https://orcid.org/0009-0000-5424-0219
Hooriehsadat AminiDepartment of Medicinal Chemistry, Faculty of Pharmacy, Tehran Medical Sciences Branch, Islamic Azad University Tehran Iran.ORCID https://orcid.org/0009-0008-7004-9447
Meng YuNMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University Guangzhou 510515 China yumeng999@smu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoporous materials (NPMs) have emerged as powerful tools in the fields of medicine, revolutionizing diagnostics, treatment, and patient care. Their unique properties address critical challenges in healthcare. Nanoporous matrices offer abundant active sites for molecular adsorption, catalysis, and interactions with biological entities. Efficient loading of therapeutic agents and biomolecules occurs due to their expansive surface area. Precise control over pore dimensions allows selective sieving, crucial for drug delivery and biosensors. Their surface chemistry and mechanical properties play pivotal roles in ensuring biocompatibility for applications like tissue scaffolds and implantable devices. In this context, the properties of NPMs, including physicochemical properties (such as crystallinity and mechanical properties), drug release and adsorption, and biological characteristics, have been comprehensively discussed. Furthermore, we also explore the multifaceted applications of NPMs, focusing on biosensing, drug delivery, wound healing, and tissue engineering.

Identifiers

PMID42291788
PMCPMC13255030

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.