Evidence map›Paper›PMID 42291642›Full record

ReviewInternational journal of clinical pediatric dentistry2026

Assessing the Effectiveness of Herbal Intracanal Irrigants in Deciduous Molars: A Systematic Review.

Mithula Raj, Deepa Gurunathan, Mahesh Ramakrishnan, Ganesh Jeevanandan, Vignesh Ravindran, Lavanya Govindaraju, Sunny Priyatham Tirupathi

Abstract readReview
In one paragraph

Review in International journal of clinical pediatric dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mithula RajDepartment of Pedodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, SIMATS Deemed University, Chennai, Tamil Nadu, India.ORCID https://orcid.org/0009-0000-6325-9165
Deepa GurunathanDepartment of Pedodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, SIMATS Deemed University, Chennai, Tamil Nadu, India.ORCID https://orcid.org/0000-0002-6014-946X
Mahesh RamakrishnanDepartment of Pedodontics and Preventive Dentistry, Saveetha Dental College and Hospitals, Chennai, Tamil Nadu, India.
Ganesh JeevanandanDepartment of Pedodontics and Preventive Dentistry, Saveetha Dental College and Hospitals, Chennai, Tamil Nadu, India.ORCID https://orcid.org/0000-0003-3631-6982
Vignesh RavindranDepartment of Pedodontics and Preventive Dentistry, Saveetha Dental College and Hospitals, Chennai, Tamil Nadu, India.
Lavanya GovindarajuDepartment of Pedodontics and Preventive Dentistry, Saveetha Dental College and Hospitals, Chennai, Tamil Nadu, India.ORCID https://orcid.org/0000-0003-0249-5513
Sunny Priyatham TirupathiDepartment of Pedodontics and Preventive Dentistry, Saveetha Dental College and Hospitals, Chennai, Tamil Nadu, India.ORCID https://orcid.org/0000-0002-2593-0090

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims and background: Pulpectomy, a crucial procedure in pediatric endodontics, involves the complete removal of infected pulp tissue and serves as a standard intervention for addressing pulp pathologies. The success of pulpectomy hinges not only on the meticulous debridement and disinfection of the root canal system but also on the judicious selection of intracanal irrigants employed during the procedure. Traditional endodontic irrigants have predominantly featured synthetic chemicals. This departure from synthetic agents to herbal irrigants is motivated by apprehensions regarding potential side effects and the environmental impact associated with conventional chemical agents. The aim of this systematic review was to assess the effectiveness of herbal intracanal irrigants compared to sodium hypochlorite (NaOCl) when used in pulpectomy of primary molars. Methods: The review's procedure was prepared in accordance with the Cochrane Handbook and the Preferred Reporting Items for Systematic Reviews and Meta-analysis 2020 Statement. A thorough search of PubMed, Google Scholar, Cochrane CENTRAL, Scopus, Web of Science, and LILACS was done for articles published between January, 2011 and June, 2024 (14 years) in order to identify all peer-reviewed research pertinent to the review's question. Only those articles that met the inclusion criteria were selected. Literature abstracts and full-text articles were analyzed in this review. A total of three articles that adhered to the eligibility requirements were ultimately chosen for inclusion. All were randomized clinical trials that evaluated the clinical and radiographic success or outcomes of herbal medicine. Results: The overall clinical and radiographic outcomes were not significantly different in all the studies. All the included studies recorded high risk of bias. Conclusion: The review concluded that herbal extracts can be considered as effective as their chemical counterparts, with the added advantage of potentially fewer side effects. Clinical significance: The efficacy of herbal irrigants in pediatric pulpectomy is comparable to that of NaOCl, with the potential advantages of increased patient acceptance, safety, and biocompatibility. How to cite this article: Raj M, Gurunathan D, Ramakrishnan M, et al. Assessing the Effectiveness of Herbal Intracanal Irrigants in Deciduous Molars: A Systematic Review. Int J Clin Pediatr Dent 2026;19(4):507-515.

Indexed as

Herbal irrigantIntracanal irrigationPrimary molarsPulpectomySodium hypochlorite

Identifiers

PMID42291642
PMCPMC13262331

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.