Evidence map›Paper›PMID 42291617›Full record

ArticleJID innovations : skin science from molecules to population health2026

Replication of acne susceptibility loci and gene-environment interactions with screen time in Singapore and Malaysia Chinese population.

Lingshu Liu, Yang Yie Sio, Dingyu Cen, Jia Yi Karen Wong, Xiangran Chen, Yee-How Say, Kavita Reginald, Fook Tim Chew

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JID innovations : skin science from molecules to population health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. From pixels to pimples.JID innovations : skin science from molecules to population health · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lingshu LiuDepartment of Biological Sciences, National University of Singapore, Singapore, Singapore.
Yang Yie SioDepartment of Biological Sciences, National University of Singapore, Singapore, Singapore.
Dingyu CenDepartment of Biological Sciences, National University of Singapore, Singapore, Singapore.
Jia Yi Karen WongDepartment of Biological Sciences, National University of Singapore, Singapore, Singapore.
Xiangran ChenDepartment of Biological Sciences, National University of Singapore, Singapore, Singapore.
Yee-How SayDepartment of Biological Sciences, National University of Singapore, Singapore, Singapore.
Kavita ReginaldDepartment of Biomedical Sciences, Sir Jeffrey Cheah Sunway Medical School, Faculty of Medical and Life Sciences, Sunway University, Subang Jaya, Malaysia.
Fook Tim ChewDepartment of Biological Sciences, National University of Singapore, Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acne vulgaris is a common chronic inflammatory skin disorder with a substantial genetic contribution. However, replication of findings from genome-wide association studies across diverse populations remains limited. In this study, we evaluated 88 previously reported acne-associated variants in 2741 acne cases and 2235 controls from the Singapore/Malaysia Cross-sequential Genetic Epidemiology Study. Two association signals were replicated at Bonferroni-corrected significance: rs1159268 near

Indexed as

Acne vulgarisGene–environment interactionGenetic susceptibilityGenome-wide association studySingle nucleotide variant

Identifiers

PMID42291617
PMCPMC13260208

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.