ReviewPakistan journal of medical sciences2026
Pregnancy outcomes after fetal reduction vs. expectant management of triplet pregnancies: A systematic review and meta-analysis.
Review in Pakistan journal of medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study critically appraises the role of embryo reduction (ER) in managing triplet pregnancies, assessing the risks of miscarriage and pre-term delivery to clarify its strengths and weaknesses. Methodology: PubMed, Embase, and Scopus were searched to identify relevant studies published up until 31 December 2025. Once identified, a random-effects meta-analysis was performed. Pooled effect sizes were reported as odds ratio (OR) or weighted mean difference (WMD) along with 95% confidence intervals. Results: Twelve studies were included. The findings from the meta-analysis revealed a significant association between expectant management and pre-term delivery (singleton: OR 0.04, 95%CI:0.02, 0.10; twins: OR 0.25, 95%CI: 0.15, 0.41), and gestational-age (in weeks) (singleton: WMD 5.53, 95%CI: 4.43, 6.64; twins: WMD 2.59, 95%CI: 2.01, 3.18). No significant association was found between ER and risk of miscarriage as well as survival rates until live birth, when compared to expectant management. Conclusions: ER in triplet pregnancies significantly reduces the risk of pre-term delivery and increases gestational age at birth compared to expectant management. However, ER does not significantly affect the risk of miscarriage or survival rates until live birth.
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