ArticlePakistan journal of medical sciences2026
Vitamin-D status in sixty adolescents with idiopathic scoliosis: An observational study.
Article in Pakistan journal of medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objectives: To investigate serum Vitamin-D levels in adolescents with idiopathic scoliosis and analyze the association between Vitamin-D levels and scoliosis severity. Methodology: This was a retrospective study. A total of 60 adolescents diagnosed with idiopathic scoliosis at Xingtai People's Hospital from September 2020 to October 2024 were enrolled for observation. Serum 25-hydroxyVitamin-D(25[OH]D) concentrations were measured, and the Cobb angle of the primary curve was determined from standing spinal radiographs. Patients were stratified into two groups according to Vitamin-D levels: the observation group (insufficient Vitamin-D) and the control group (sufficient Vitamin-D). Statistical analyses were performed using the software Prism, with independent t-tests and correlation analyses. Results: Among patients with Vitamin-D deficiency or insufficiency (25[OH]D < 50 nmol/L), 11 exhibited a Cobb angle > 15°, whereas only two patients with sufficient Vitamin-D levels (25[OH]D 50-250 nmol/L) had a Cobb angle > 15°. A significant negative correlation was observed between serum 25(OH)D concentration and scoliosis severity ( Conclusion: Vitamin-D deficiency may be associated with the development of adolescent idiopathic scoliosis. Adequate Vitamin-D supplementation could help mitigate curve progression and reduce scoliosis severity.
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