ArticleFrontiers in cardiovascular medicine2026
Myocardial work efficiency in children with Wolff-Parkinson-White preexcitation before and after accessory pathway ablation.
Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and objective: Ventricular preexcitation alters the electromechanical activation sequence and may induce left ventricular (LV) contractile discoordination and pathologic remodeling. We aimed to evaluate LV myocardial work (MW) before and after accessory pathway (AP) ablation and to compare it to controls in a prospective observational study. Methods: MW calculation was performed in 37 pediatric patients with Wolff-Parkinson-White preexcitation before and within 24 h after catheter ablation using a commercial software. MW was calculated as the area under pressure-strain loop derived from speckle tracking echocardiography and blood pressure. Thirty healthy age- and weight-matched individuals were used as controls. Results: Before ablation LV ejection fraction (mean 55.3 in patients vs. 59.3% in controls, Conclusion: Ventricular preexcitation is associated with decreased LV MW efficiency which correlates negatively with the degree of preexcitation and improves early after ablation. Wasted work in asymptomatic preexcitation may be considered when assessing the potential for pathologic LV remodeling or discussing the indication for prophylactic ablation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.