ArticleFrontiers in cardiovascular medicine2026
Late infection of thoracic aortic stent graft with aerodigestive fistula: a case series and narrative literature review.
Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To describe the clinical presentation, diagnostic process, and surgical outcomes of late thoracic aortic stent graft infection (ASGI) with aerodigestive fistula. Methods: We retrospectively analyzed three late ASGI patients admitted between 2015 and 2025, supplemented by a narrative literature review. Case 1 presented with mediastinal abscess and aorto-esophageal fistula; Case 2 with aorto-esophageal and aorto-tracheal fistula; Case 3 with aorto-tracheoesophageal fistula. Results: All three patients underwent surgical intervention: abscess debridement and drainage (Case 1); re-intervention with covered stent, esophageal resection, and lobectomy (Case 2); and staged aortic bypass (Case 3). The 30-day postoperative mortality rate was 1/3 (33.3%), and the 1-year mortality rate was 3/3 (100%). Conclusion: Late ASGI complicated by aerodigestive fistula carries an extremely poor prognosis. Early recognition and timely consideration of definitive source control may be important, but optimal management remains challenging.
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