ReviewFrontiers in cellular and infection microbiology2026
The dialogue between breast cancer and microorganisms.
Review in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Breast cancer is a complex pathological process involving multiple factors and stages, characterized by pronounced molecular and phenotypic heterogeneity. Its global incidence and mortality rates have shown a continuous upward trend. With the advancement of microbiome research, microbial communities have been recognized as key determinants influencing host health and disease states. Increasing evidence suggests a close association between breast tissue-resident and systemic microbiota and the initiation and progression of breast cancer. Specifically, microorganisms may be associated with abnormal proliferation and malignant transformation of mammary epithelial cells through diverse mechanisms, including the modulation of estrogen metabolism, production of bioactive metabolites, induction of chronic inflammation, and remodeling of the tumor microenvironment. In addition, certain microbes may directly interact with host cells, potentially inducing DNA damage and contributing to the transition from normal to malignant phenotypes. This review systematically summarizes the origins and compositional characteristics of the breast microbiota, with a particular focus on current evidence regarding its roles in breast cancer initiation, progression, metastasis, therapeutic response, and prognosis. Currently, the majority of evidence originates from cross-sectional studies and
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.