ArticleFrontiers in cellular and infection microbiology2026
Clinical characteristics of
Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
Objective: To investigate the clinical characteristics and identify risk factors for severe Methods: This retrospective study included 39 non-HIV PJP patients diagnosed by next-generation sequencing (NGS) of bronchoalveolar lavage fluid (BALF) at Taizhou Municipal Hospital between June 2019 and March 2025. Patients were divided into severe (n=18) and non-severe (n=21) groups based on disease severity. Continuous variables were analyzed using Student's t-test or Mann-Whitney U test, while categorical variables were compared with Fisher's exact test. Variables showing statistical significance (P<0.05) were subsequently included in multivariable logistic regression analysis to identify differences in clinical characteristics between the two groups. Results: The mean age of the entire cohort was 62.59 ± 12.59 years, and 64.10% (25/39) were male. The severe group had significantly higher case-fatality rate than the non-severe group (61.1% vs. 0%, Conclusions:
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