Evidence map›Paper›PMID 42291300›Full record

ArticleFrontiers in cellular and infection microbiology2026

Optimization of colonoscope bedside precleaning protocol: an orthogonal experimental study.

Bingru Li, Jinpeng Jiang, Yingying Wang, Qihan Wu, Yuan Sheng, Ningning Li, Mengdan Ye, Wen Li, Wei Cai

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PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bingru LiDepartment of Digestive Endoscopy Center, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Jinpeng JiangDepartment of Digestive Endoscopy Center, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Yingying WangDepartment of Digestive Endoscopy Center, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Qihan WuDepartment of Digestive Endoscopy Center, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Yuan ShengDepartment of Infection Management Office, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Ningning LiDepartment of Digestive Endoscopy Center, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Mengdan YeDepartment of Digestive Endoscopy Center, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Wen LiDepartment of Digestive Endoscopy Center, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Wei CaiDepartment of Digestive Endoscopy Center, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study utilized an orthogonal experimental design to optimize the bedside precleaning protocol for colonoscopes. It evaluated the correlation between adenosine triphosphate (ATP) bioluminescence testing and microbial culture results, thereby establishing an evidence-based foundation for quality control in endoscopy. Methods: Four factors affecting colonoscope bedside precleaning were selected, each with three levels, and arranged into nine protocols using an L9(3 Results: Factors A (types of detergents) and C (suction duration) demonstrated statistically significant effects on post-precleaning ATP values and microbial counts (P = 0.035 and P = 0.048, respectively), with alkaline solution (A Conclusions: The optimized colonoscope bedside precleaning protocol for reducing biopsy channel contamination includes: alkaline solution (A

Indexed as

ColonoscopesDisinfectionAdenosine TriphosphateColony Count, MicrobialHumansAdenosine Triphosphatebedside precleaningdecontaminationendoscope reprocessing colonoscopeexperimentalorthogonal

Identifiers

PMID42291300
PMCPMC13253387

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.