Evidence map›Paper›PMID 42291215›Full record

ArticleiScience2026

A socio-hydro-epidemiological model for simulating trade-off between dengue infections, water shortages, and adaptive behavior.

Maurizio Mazzoleni, Francesco Defilippo, Carlo Torti, Eugenia Quiros-Roldan, Elena Raffetti

Abstract read
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maurizio MazzoleniInstitute for Environmental Studies, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Francesco DefilippoIstituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia-Romagna "Bruno Ubertini" (IZSLER), Brescia, Italy.
Carlo TortiDipartimento di Sicurezza e Bioetica - Sezione di Malattie Infettive, Università Cattolica del Sacro Cuore, Rome, Italy.
Eugenia Quiros-RoldanDepartment of Clinical and Experimental Sciences, Unit of Infectious and Tropical Diseases, University of Brescia and ASST Spedali Civili di Brescia, 25123 Brescia, Italy.
Elena RaffettiUnit of Infectious and Tropical Diseases, ASST Spedali Civili di Brescia, 25123 Brescia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dengue and drought severity are rising worldwide, with drought responses shaping mosquito breeding conditions in cities. Current modeling approaches do not couple household water-use behavior, climate extremes, and vector-borne disease transmission. Here, we developed a system dynamics model that links dengue transmission, human-water interactions, multiple adaptation strategies, and social behavior in a synthetic city. We compared three adaptation pathways: dengue-focused, drought-focused, and co-adaptation guided by social awareness. Results show that adaptation choices strongly affect awareness, water shortages, mosquito abundance, and human infections. Drought-focused adaptation reduces average water shortages, but prolonged standing water in rainwater tanks increases mosquito growth and dengue transmission. Co-adaptation retains drought buffering while limiting favorable habitat for vector growth. Changes in drought-awareness decay can influence dengue outbreaks more strongly than changes in dengue-awareness decay. These results highlight the value of coordinated drought and dengue management for reducing health risks while maintaining water security under climate change.

Indexed as

environmental healthenvironmental science

Identifiers

PMID42291215
PMCPMC13264125

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.