Evidence map›Paper›PMID 42291206›Full record

ArticleiScience2026

Posterior shift of Shh-Fgf signaling in axolotl limb regeneration drives sequential digit formation.

Saya Furukawa, Sakiya Yamamoto, Haruki Nakayama, Ayaka Ohashi, Akira Satoh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Saya FurukawaGraduate School of Environmental, Life, Natural Science and Technology, Okayama University, Okayama, Okayama Prefecture, Japan.
Sakiya YamamotoGraduate School of Environmental, Life, Natural Science and Technology, Okayama University, Okayama, Okayama Prefecture, Japan.
Haruki NakayamaGraduate School of Environmental, Life, Natural Science and Technology, Okayama University, Okayama, Okayama Prefecture, Japan.
Ayaka OhashiGraduate School of Environmental, Life, Natural Science and Technology, Okayama University, Okayama, Okayama Prefecture, Japan.
Akira SatohGraduate School of Environmental, Life, Natural Science and Technology, Okayama University, Okayama, Okayama Prefecture, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Do conserved morphogen modules generate a given form only via a single spatiotemporal deployment, or can alternative deployments yield the same morphology? Axolotl limb regeneration provides a tractable test bed. SHH and FGF8, universally used in limb formation across vertebrates, also operate in axolotl, although the spatial domain of

Indexed as

Developmental biologyEvolutionary biologyMolecular biology

Identifiers

PMID42291206
PMCPMC13259619

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.