ArticleCytoJournal2026
A case of inappropriate thyroid-stimulating hormone secretion syndrome after thalidomide treatment.
Article in CytoJournal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Thalidomide is used for the management of several diseases, including the treatment of certain dermatological conditions. We report a case of thyroid dysfunction, characterized by a high serum thyroid-stimulating hormone (TSH) level accompanied by high free triiodothyronine (FT3) and free thyroxine (FT4), in a patient with preexisting hypothyroidism and human immunodeficiency virus (HIV) infection during thalidomide treatment. The case provides a novel pattern of thyroid dysfunction induced by thalidomide, differing from classical thyroid disease. We recommended a measurement of baseline thyroid function and TRAb before thalidomide treatment, every 2 weeks during the initial 1-3 months, and then monthly.
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