Evidence map›Paper›PMID 42291016›Full record

ReviewInternational journal of clinical pediatric dentistry2026

Cold Atmospheric Plasma in Pediatric Dentistry: A Paradigm Shift toward Antibiotic-free Minimally Invasive Care.

Prachi Kumari, Kanika S Dhull, Brahmananda Dutta, Abinash Mohapatra, Indira M Devraj, Singi Rj Reddy

Abstract readReview
In one paragraph

Review in International journal of clinical pediatric dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Prachi KumariDepartment of Pedodontics and Preventive Dentistry, Kalinga Institute of Dental Sciences, Bhubaneswar, Odisha, India.ORCID https://orcid.org/0009-0005-3061-2416
Kanika S DhullDepartment of Pedodontics and Preventive Dentistry, Kalinga Institute of Dental Sciences, Bhubaneswar, Odisha, India.ORCID https://orcid.org/0000-0002-0002-8084
Brahmananda DuttaDepartment of Pedodontics and Preventive Dentistry, Kalinga Institute of Dental Sciences, Bhubaneswar, Odisha, India.ORCID https://orcid.org/0000-0003-3155-6979
Abinash MohapatraDepartment of Pedodontics and Preventive Dentistry, Kalinga Institute of Dental Sciences, Bhubaneswar, Odisha, India.ORCID https://orcid.org/0000-0002-7387-0870
Indira M DevrajDepartment of Pedodontics and Preventive Dentistry, JSS Dental College, JSS University, Mysuru, Karnataka, India.ORCID https://orcid.org/0000-0002-2296-1756
Singi Rj ReddyDepartment of Pedodontics and Preventive Dentistry, Kalinga Institute of Dental Sciences, Bhubaneswar, Odisha, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: A revolutionary alternative to antibiotics, cold atmospheric plasma (CAP) provides a potent means of addressing the worldwide problem of antibiotic resistance. Its potential use in pediatric dentistry is yet mainly untapped, which emphasizes the necessity of focused study. Materials and methods: Using a thorough examination of 20 well-reviewed publications published between 2016 and 2025, this in-depth study looks at the antibacterial qualities, modes of action, safety concerns, and clinical uses of CAP in pediatric dental care. In order to rapidly and effectively eradicate microorganisms, CAP works by generating reactive oxygen and nitrogen species (RONS), which damage bacterial cell membranes and biofilms. Results: According to this review, CAP may be used in dentistry as a less invasive option to traditional antibiotics because it eases anxiety and does not add to the growing issue of resistance. Conclusion: Despite its positive advantages, there are still several obstacles to overcome, like the requirement for cost-effectiveness, device standardization, and regulatory approval for kid-specific devices. Future research should concentrate more on improving CAP technology, investigating how it might be used with other dental advancements, and evaluating its long-term impacts on oral health results. How to cite this article: Kumari P, Dhull KS, Dutta B,

Indexed as

Antibiotic resistanceBiofilm removalCold atmospheric plasmaMinimally invasive dentistryPediatric dentistry

Identifiers

PMID42291016
PMCPMC13262311

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.