Evidence map›Paper›PMID 42291015›Full record

ArticleInternational journal of clinical pediatric dentistry2026

Comparative Evaluation of Mineral Trioxide Aggregate, Biodentine, and Calcium Hydroxide for Apical Closure in Nonvital Immature Teeth: A Randomized Controlled Trial.

Abraham Sabu, R Ramesh

Abstract read
In one paragraph

Article in International journal of clinical pediatric dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Abraham SabuDepartment of Pediatric Dentistry, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences, SIMATS University, Chennai, Tamil Nadu, India.
R RameshDepartment of Pediatric Dentistry, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences, SIMATS University, Chennai, Tamil Nadu, India.ORCID https://orcid.org/0000-0002-1957-3867

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Managing nonvital immature teeth with open apices poses clinical challenges, particularly in achieving predictable apical closure. Aim: To compare the efficacy of mineral trioxide aggregate (MTA), Biodentine, and calcium hydroxide in promoting apical closure in nonvital immature anterior teeth. Materials and methods: This randomized controlled trial involved 60 patients aged 8-14 years with nonvital immature maxillary anterior teeth. Participants were divided into three groups: group I-MTA, group II-Biodentine, and group III-calcium hydroxide. Standardized treatment protocols were followed, and radiographic assessments were conducted at baseline, 3 months, 6 months, and 12 months to evaluate apical closure. Results: Group I (MTA) and group II (Biodentine) demonstrated significantly faster apical closure than group III (calcium hydroxide) ( Conclusion: Biodentine is an effective material for promoting faster apical closure in nonvital immature teeth, followed closely by MTA. Calcium hydroxide required a longer duration to achieve comparable results. How to cite this article: Sabu A, Ramesh R. Comparative Evaluation of Mineral Trioxide Aggregate, Biodentine, and Calcium Hydroxide for Apical Closure in Nonvital Immature Teeth: A Randomized Controlled Trial. Int J Clin Pediatr Dent 2026;19(5):575-587.

Indexed as

BiodentineCalcium hydroxideImmature toothMineral trioxide aggregatePulp therapy

Identifiers

PMID42291015
PMCPMC13262122

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.