ArticleInternational journal of clinical pediatric dentistry2026
Comparative Evaluation of Remineralizing Agents on Hypersensitivity Scores in Molar Incisor Hypomineralization-affected Teeth: A Randomized Clinical Trial.
Article in International journal of clinical pediatric dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: This randomized clinical trial aimed to evaluate and compare the efficacy of four desensitizing agents-fluoride varnish (Duraphat), FluoriMax varnish (Elevate), surface prereacted glass-ionomer (S-PRG) filler (Shofu), and silver diamine fluoride (SDF)-in managing hypersensitivity in molar incisor hypomineralization (MIH)-affected teeth. Materials and methods: A total of 80 children aged between 6 and 12 years, each presenting with at least one incisor and one first permanent molar showing yellow or brown MIH opacities, were selected for the study. The participants were randomly divided into four treatment groups-Duraphat, FluoriMax, S-PRG, and SDF. Hypersensitivity levels were assessed using the Schiff Cold Air Sensitivity Scale (SCASS) at baseline and then reevaluated at 1, 3, and 6 months following treatment. Intergroup differences were analyzed using ANOVA, followed by Tukey's honestly significant difference (HSD) Results: All groups demonstrated a significant reduction in mean SCASS scores over the 6-month period ( Conclusion: SDF demonstrated the greatest reduction in hypersensitivity in teeth affected by MIH. This was followed by S-PRG and FluoriMax, while fluoride varnish (Duraphat) was the least effective among all agents tested. Clinical significance: This study highlights the application of newer remineralizing agents, particularly SDF and S-PRG, in relieving hypersensitivity associated with MIH in children, thereby augmenting patient comfort and promoting the longevity of permanent dentition. How to cite this article: Thakur D, Kalra G, Goyal V,
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