Evidence map›Paper›PMID 42290961›Full record

ArticleAnimal nutrition (Zhongguo xu mu shou yi xue hui)2026

Zinc oxide quantum dots as an alternative to conventional ZnO: Physicochemical characterization and its application in weaned piglets.

Chan Liang, Xintao Wang, Daiwen Chen, Gang Tian, Jun He, Ping Zheng, Jie Yu, Junning Pu, Wendan Zhou, Bing Yu

Abstract read
In one paragraph

Article in Animal nutrition (Zhongguo xu mu shou yi xue hui), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chan LiangKey Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Chengdu 611130, Sichuan, China.
Xintao WangKey Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Chengdu 611130, Sichuan, China.
Daiwen ChenKey Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Chengdu 611130, Sichuan, China.
Gang TianKey Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Chengdu 611130, Sichuan, China.
Jun HeKey Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Chengdu 611130, Sichuan, China.
Ping ZhengKey Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Chengdu 611130, Sichuan, China.
Jie YuKey Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Chengdu 611130, Sichuan, China.
Junning PuKey Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Chengdu 611130, Sichuan, China.
Wendan ZhouKey Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Chengdu 611130, Sichuan, China.
Bing YuKey Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Chengdu 611130, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-dose zinc oxide (ZnO) is effective in preventing diarrhea in piglets, but its use is limited by several concerns, including impaired intestinal barrier function, increased bacterial resistance, and the risks of heavy metal residues and environmental pollution. This study aimed to investigate whether zinc oxide quantum dots (ZnO QDs), a novel nanomaterial with diameters of less than 10 nm, could serve as an alternative to ZnO. In vitro, ZnO QDs were used to characterize the structure and evaluate antibacterial activity. In vivo, a total of 150 piglets (24 ± 1 d old, 7.45 ± 0.41 kg weight) were randomly divided into five groups: negative control group (CON), positive control group (ZnO; 1500 mg/kg Zn as ZnO), and 3 levels of ZnO QDs groups (250, 500, or 750 mg/kg Zn as ZnO QDs). Each group consisted of 10 replicates of 3 piglets for a 28-d trial. Results showed that ZnO QDs (size = 3.82 ± 0.38 nm, specific surface area = 17.65 m

Indexed as

Antibacterial activityDiarrheaIntestinal microbiotaPigletZinc metabolismZinc oxide quantum dot

Identifiers

PMID42290961
PMCPMC13255035

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.