ArticleAnimal nutrition (Zhongguo xu mu shou yi xue hui)2026
Maternal methionine supplementation regulates skeletal muscle development through N
Article in Animal nutrition (Zhongguo xu mu shou yi xue hui), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Maternal nutrition is a key determinant of offspring growth, as poultry embryonic muscle depends entirely on yolk-derived nutrients. Methionine (Met), a vital amino acid and methyl donor in one-carbon metabolism, regulates myogenesis, yet its epigenetic mechanisms remain poorly understood. Two independent maternal experiments and corresponding offspring trials were performed. For the maternal trials, Experiment 1 included 720 WOD188 broiler breeder hens (41-week-old, initial body weight [BW]: 4500 ± 300 g) randomly assigned to 3 treatments with 8 replicates of 30 birds each, and fed a basal diet and basal diets supplemented with 0.15% DL-Met or 0.17% 2-hydroxy-4-(methylthio)-butanoate (HMTBA) for 7 weeks. Experiment 2 used 480 41-week-old hens (initial BW: 4100 ± 285 g) randomly allocated to 3 treatments with 8 replicates of 20 birds each, and fed a basal diet and the basal diets supplemented with 0.15% DL-Met or 0.09% choline chloride for 5 weeks. For the offspring trials, fertilized eggs were incubated in both experiments. A total of 240 1-d-old male chicks (initial BW: 42.5 ± 2.5 g) per trial were grouped by maternal treatment and reared for 6 weeks (Exp. 1) or 14 d (Exp. 2, for N
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