Evidence map›Paper›PMID 42290917›Full record

ArticleCase reports in orthopedics2026

Spinal Cord Compression due to Pyothorax-Associated Lymphoma: A Rare Presentation of EBV-Positive Diffuse Large B-Cell Lymphoma.

Keita Yanagisawa, Junya Saito, Hiroshi Takahashi, Arata Nakajima, Koichi Nakagawa

Abstract read
In one paragraph

Article in Case reports in orthopedics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Keita YanagisawaDepartment of Orthopaedic Surgery, Toho University Sakura Medical Center, Chiba, Japan, toho-u.ac.jp.
Junya SaitoDepartment of Orthopaedic Surgery, Toho University Sakura Medical Center, Chiba, Japan, toho-u.ac.jp.ORCID https://orcid.org/0000-0001-9170-9135
Hiroshi TakahashiDepartment of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan, tsukuba.ac.jp.ORCID https://orcid.org/0000-0002-3497-4802
Arata NakajimaDepartment of Orthopaedic Surgery, Toho University Sakura Medical Center, Chiba, Japan, toho-u.ac.jp.ORCID https://orcid.org/0000-0002-6626-5293
Koichi NakagawaDepartment of Orthopaedic Surgery, Toho University Sakura Medical Center, Chiba, Japan, toho-u.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pyothorax-associated lymphoma (PAL) is an Epstein-Barr virus (EBV)-positive diffuse large B-cell lymphoma developing in the setting of long-standing chronic pyothorax. Neurological involvement due to spinal invasion is extremely rare. Case Presentation: An 87-year-old woman with a remote history of pulmonary tuberculosis presented with rapidly progressive paraplegia. Imaging demonstrated chronic right pyothorax with a dorsal epidural mass compressing the spinal cord, continuous with a pleural lesion. A biopsy confirmed EBV-positive diffuse large B-cell lymphoma, consistent with PAL. Surgery was considered but declined by the patient and the family. Therefore, the patient was treated with corticosteroids followed by two cycles of R-CHOP chemotherapy; however, no neurological improvement was observed. Conclusion: This case highlights a rare neurological manifestation of PAL. Clinicians should consider lymphoma infiltration in elderly patients with chronic pyothorax who develop new neurological deficits. Early MRI and biopsy are crucial for accurate diagnosis and management.

Identifiers

PMID42290917
PMCPMC13254235

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.