ArticleCase reports in hematology2026
Synchronous Presentation of Chronic Myelomonocytic Leukemia and Multiple Myeloma in a Treatment-Naïve Patient.
Article in Case reports in hematology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Synchronous Presentation of Chronic Myelomonocytic Leukemia and Multiple Myeloma in a Treatment-Naïve Patient.Case reports in hematology · 2026Article
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Authors and funding
6 authors.
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Abstract
Background: Chronic myelomonocytic leukemia (CMML) is a clonal myelodysplastic/myeloproliferative neoplasm characterized by persistent peripheral blood monocytosis and dysplastic bone marrow morphology. Multiple myeloma (MM) is a plasma cell malignancy defined by clonal plasma cell proliferation and myeloma-defining events. The synchronous occurrence of CMML and MM is exceptionally rare, particularly in treatment-naïve and relatively young patients. Case Presentation: We present a 42-year-old-male presenting with progressive fatigue and leukocytosis. Laboratory evaluation revealed marked absolute monocytosis (16.4 × 10 Conclusions: This case describes a rare concurrent presentation of CMML and MM in a young, treatment-naïve patient. The combination of persistent monocytosis, dysplastic marrow findings, and monosomy 7 supported the presence of clonal myeloid process coexisting with plasma cell myeloma. Recognizing concurrent hematologic malignancies is essential, as diagnostic overlap and treatment interactions present substantial management challenges. Additional molecular characterization of similar cases may elucidate potential pathogenetic connections and guide tailored therapeutic approaches.
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