Evidence map›Paper›PMID 42290810›Full record

ArticleClinical case reports2026

Lansoprazole-Induced Microscopic Colitis Mimicking Anticancer Drug-Related Diarrhea During Lenvatinib and Pembrolizumab Combination Therapy: A Case Report.

Shinichi Maruyama, Takuro Hirano, Kazuhiro Fuchinoue, Yoshikiyo Akasaka, Takanori Yoshida, Hiroshi Kanno, Masaru Kato

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In one paragraph

Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shinichi MaruyamaDepartment of Pharmacy Saiseikai Yokohamashi Tobu Hospital Yokohama City Kanagawa Japan.ORCID https://orcid.org/0009-0008-1386-8112
Takuro HiranoDepartment of Obstetrics and Gynecology Saiseikai Yokohamashi Tobu Hospital Yokohama City Kanagawa Japan.
Kazuhiro FuchinoueDepartment of Gastroenterology Saiseikai Yokohamashi Tobu Hospital Yokohama City Kanagawa Japan.
Yoshikiyo AkasakaDepartment of Surgical Pathology Saiseikai Yokohamashi Tobu Hospital Yokohama City Kanagawa Japan.
Takanori YoshidaDepartment of Obstetrics and Gynecology Saiseikai Yokohamashi Tobu Hospital Yokohama City Kanagawa Japan.
Hiroshi KannoDepartment of Pharmacy Saiseikai Yokohamashi Tobu Hospital Yokohama City Kanagawa Japan.
Masaru KatoDepartment of Bioanalytical Chemistry Showa Medical University Graduate School of Pharmacy Tokyo Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Persistent diarrhea during anticancer therapy may not be attributable to anticancer agents. Our patient presented with diarrhea during lenvatinib-pembrolizumab therapy, likely caused by lansoprazole-induced microscopic colitis. Even when symptoms closely resemble anticancer drug or immune-related colitis, drug-induced colitis due to concomitant medications, including proton pump inhibitors, should be considered.

Indexed as

diarrheaendometrial carcinomaimmune checkpoint inhibitormicroscopic colitisproton pump inhibitortyrosine kinase inhibitor

Identifiers

PMID42290810
PMCPMC13261079

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.