ArticleFrontiers in pediatrics2026
Preoperative myocardial strain, mesenteric resistance, and aortopulmonary collateral flow are associated with pleural effusion duration after fontan completion.
Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: The contribution of aortopulmonary collateral (APC) flow to pleural effusion (PE) after total cavopulmonary connection (TCPC) remains unclear. Excessive APC flow may alter mesenteric perfusion and increase ventricular volume load. We evaluated echocardiographic and mesenteric flow parameters as predictors of PE duration and their association with magnetic resonance imaging (MRI)-derived APC flow. Methods: We prospectively studied patients with single ventricle (SV) physiology referred for TCPC at the Children's Heart Centers in Lund and Gothenburg, the two referral centers for pediatric cardiac surgery in Sweden. Preoperative assessment included 2D longitudinal strain from four-chamber (4CH) view and 3D global longitudinal strain (GLS), Doppler derived resistance index (RI) in the superior mesenteric artery (SMA) and cardiac MRI. APC flow was quantified using two MRI-based methods: (A) pulmonary venous minus arterial flow, and (B) aortic flow minus total caval flow, both indexed to body surface area. Results: Thirty-four patients (median age at TCPC 2.8 (range:1.8-8.2) years; female: 44%; dominant right ventricle: 56%) were included. PE duration was significantly associated with higher 4CH-longitudinal strain ( Discussion: Prolonged pleural effusion after TCPC is associated with APC burden, echocardiographic markers of ventricular volume loading, and impaired mesenteric perfusion. GLS and SMA resistance index may reflect APC-related hemodynamic disturbance and serve as accessible, non-invasive surrogates to help identify patients at risk for adverse early TCPC outcomes.PE duration after TCPC is associated with echocardiographic markers of volume overload and impaired mesenteric perfusion. GLS and SMA RI may serve as non-invasive surrogates for APC burden measured via MRI.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.