ArticleFrontiers in pediatrics2026
Long-term epidemiological patterns of pediatric infectious diseases in an urban district of Shanghai, 2015-2023.
Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Understanding temporal and epidemiological patterns of pediatric infectious diseases is essential for developing targeted prevention strategies. This study investigated long-term incidence trends and epidemiological characteristics of notifiable infectious diseases among children in Xuhui District, Shanghai, from 2015 to 2023. Methods: Surveillance data for children aged 0-17 years were obtained from the National Notifiable Disease Reporting System (NNDRS). Joinpoint regression was applied to identify temporal trends and significant inflection points. Age-specific distributions were analyzed and seasonal patterns were visualized using radar charts. Results: From 2015 to 2023, a total of 27,940 pediatric cases involving 23 notifiable infectious diseases were reported, corresponding to an average annual incidence of 2,421.68 per 100,000 children. Joinpoint regression identified a significant inflection point in 2021. Overall incidence declined during 2015-2021 (APC = -11.71%, 95% CI: -30.10 to -1.50, Conclusion: Pediatric infectious disease epidemiology in Xuhui District underwent substantial changes across the pre-pandemic and post-pandemic periods. The sharp rise after 2021 was largely attributable to COVID-19, rather than a uniform rebound of all infectious diseases. Distinct temporal patterns across respiratory, enteric, and other infections underscore the importance of pathogen-specific transmission characteristics and age-related exposure in shaping long-term trends. These findings highlight the need for targeted, age-appropriate prevention strategies and sustained surveillance in the post-pandemic era.
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