ArticleFrontiers in pediatrics2026
Analysis of influencing factors for progression from type 2 to type 1 in retinopathy of prematurity.
Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To investigate factors associated with the progression of Retinopathy of Prematurity(ROP). Methods: A retrospective analysis was performed on 148 ROP infants. All cases were classified into type 1 and type 2 ROP according to the ETROP criteria, and those progressing from type 2 to type 1 were defined as progressive type (prog-type). Intergroup differences and relevant factors for prog-type were analyzed. Results: Among the 148 infants with ROP, 31 (20.9%) were type 1 ROP, 91 (61.5%) were type 2 ROP, and 26 (17.6%) were prog-type. Univariate analyses revealed significant differences among the three groups in gestational age (GA), birth weight(BW), delivery mode, 5-min Apgar score, hood/nasal cannula oxygen therapy(HH/MNCO) duration, non-invasive ventilation(NIV) duration, and presence of bronchopulmonary dysplasia(BPD) (all Conclusion: Different ROP groups exhibit distinct clinical characteristics. Lower GA, low BW, prolonged NIV and BPD were correlated with prog-type. Among C-section infants, prog-type was less common than type 1, whereas type 2 was more common than type 1. After multinomial adjustment, GA and HH/MNCO duration remained independently associated with prog-type, which may help clinical risk assessment and individualized intervention.
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