Evidence map›Paper›PMID 42290699›Full record

ArticleResuscitation plus2026

Physiological changes after deflation of Resuscitative Endovascular Balloon Occlusion of the Aorta following Automated Head-up Position Cardiopulmonary Resuscitation: a post-hoc analysis.

N Segond, J Moore, P Pourzand, B Salverda, M Suresh, K Bachista, A Johnson, S T Youngquist, G Debaty, K Lurie

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Resuscitation plus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

N SegondUniv. Grenoble Alpes, Emergency Department and Mobile Intensive Care Unit, CNRS, UMR 5525, VetAgro Sup, Grenoble INP, TIMC, 38000 Grenoble, France.
J MooreDepartment of Emergency Medicine, University of Minnesota, Minneapolis, MN, USA.
P PourzandDepartment of Emergency Medicine, Lehigh Valley Health Network, Bethlehem, PA, USA.
B SalverdaHennepin Healthcare Research Institute, Minneapolis, MN, USA.
M SureshHennepin Healthcare Research Institute, Minneapolis, MN, USA.
K BachistaMayo Clinic School of Health Sciences, Mayo Clinic in Florida, Jacksonville, FL, USA.
A JohnsonDepartment of Emergency Medicine, University of Utah Health, Salt Lake City, UT, USA.
S T YoungquistDepartment of Emergency Medicine, University of Utah Health, Salt Lake City, UT, USA.
G DebatyUniv. Grenoble Alpes, Emergency Department and Mobile Intensive Care Unit, CNRS, UMR 5525, VetAgro Sup, Grenoble INP, TIMC, 38000 Grenoble, France.
K LurieDepartment of Emergency Medicine, University of Minnesota, Minneapolis, MN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Use of Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) and the automated head-up position (AHUP) have increasingly both been separately reported during cardiopulmonary resuscitation (CPR). The optimal hemodynamic management of REBOA balloon deflation after the return of spontaneous circulation (ROSC) is unknown. We hypothesized that partial deflation of REBOA rather than full deflation after ROSC would result in better hemodynamic parameters. Methods: After 10 min of untreated ventricular fibrillation, AHUP-CPR was performed on 20 pigs (weighting ∼40 kg). After 36 min, a REBOA balloon was inflated. After ROSC (13 pigs) REBOA deflation was initiated in one of two ways: complete (100%) or partial (50%) deflation. The primary endpoint was mean difference in mean aortic pressure (MAP) compared one minute before and one minute after REBOA deflation. Secondary endpoints were mean difference in cerebral perfusion (CerPP) and coronary perfusion (CorPP) pressures (in mmHg). Data were compared using Mann-Whitney Results: After ROSC the mean difference in MAP before and after deflation was 38.5 mmHg (95%CI: 17.0-60.0) with complete deflation versus 7.0 (95%CI: 1.8-12.3) with partial deflation ( Conclusion: In this porcine model of prolonged AHUP-CPR, partial REBOA balloon deflation resulted in superior hemodynamics compared with complete deflation.

Indexed as

Cardiopulmonary resuscitationEndovascular proceduresIntra-aortic balloonResuscitationResuscitative endovascular balloon occlusion of the aorta

Identifiers

PMID42290699
PMCPMC13264273

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.