Evidence map›Paper›PMID 42290655›Full record

ArticleGenes & diseases2026

Hypoxia-induced m

Xianzhi Gao, Bian Shu, Diguang Wen, Jiao Lu, Hua Song, Ziyi Sheng, Yu You, Zuojin Liu

Abstract read
In one paragraph

Article in Genes & diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xianzhi GaoDepartment of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Bian ShuDepartment of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Diguang WenDepartment of Hematology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Jiao LuDepartment of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Hua SongDepartment of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Ziyi ShengDepartment of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Yu YouDepartment of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Zuojin LiuDepartment of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increasing evidence indicates that the galectin family played a significant role in tumor progression and is closely related to the hypoxic microenvironment within tumor tissues. However, the regulatory mechanisms behind this process are unexplored. In this study, we found that Gal-1 expression was significantly up-regulated in hepatocellular carcinoma (HCC) tissues and was closely associated with poor prognosis of patients. Intervention of Gal-1 at the cellular level significantly inhibited the malignant phenotype of hepatoma cells. For the first time, we discovered that Gal-1 was regulated by m

Indexed as

ALKBH5Galectin-1Hepatocellular carcinomaHIF-1αYTHDF2

Identifiers

PMID42290655
PMCPMC13254588

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.